The Claritin Effect; Prescription for Profit - The New York Times

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The Claritin Effect; Prescription for Profit - The New York Times
Mar 11, 2001 ... There are no villains, no broken laws -- just an enormous expenditure of money, ... All the antihistamine drugs, new and old, are plagued by high placebo effects. ..... ''The Claritin campaign, along with Viagra, Prilosec and a few other ... Generic drug companies typically gear up to produce a cheap version of ...

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You can expect to receive your first savings tips and price alerts soon. Yet critics point out that direct-to-consumer advertising illustrates an embarrassing paradox marketing may be most indispensable in categories where new drugs may actually be less innovative. .

In a daring move closely watched by the rest of the industry, schering-plough poured 322 million into pitching claritin to consumers in 19, far more than any other brand, according to the national institute for health care management foundation, a nonprofit group in washington. Some critics make the case that since hatch-waxman, an inordinate amount of innovation has been displaced from research to litigation strategies. It had a huge impact, because everybody is watching everybody else very closely.

And straus had argued, to the satisfaction of at least some people on the committee, that while the drug might be more effective than placebo, it was not a whole lot more effective. Generic drug companies typically gear up to produce a cheap version of a drug about five to seven years before a patent is due to expire. When everyone else jumps in six months later, the price will fall off a cliff.

Please seek medical advice before starting, changing or terminating any medical treatment. To treat full-blown allergy symptoms with an antihistamine, he continued, was pharmacologically irrational. The little white pill was easy to swallow and had to be taken only once a day.

But i heard a different view from a pharmacologist who, although insisting on anonymity, was familiar with these unfolding events. In fact, the company thought it had one in a compound called azatadine. Drug companies routinely submit notebooks of dictionary girth full of experimental results establishing a drugs safety profile, first in animals and then in human subjects.

What to do in a crisis? Market! Several days later, as the companys stock plunged and attorneys hustled to organize shareholder lawsuits, schering-plough announced big new consumer education and pharmacy programs for claritin -- the largest and most comprehensive allergy initiative of its kind. Ive been battered by seasonal allergies all my life but relied on family doctors and, more recently, primary-care physicians for relief. Schering to test a higher dose of loratadine but lacked the regulatory authority to mandate it. Straus didnt doubt that loratadine worked as an antihistamine, he said he just doubted that it worked at the 10-milligram dose. If the generic industry is beginning to mature, as some maintain, one of the main factors in that process has been, oddly, schering-plough.


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Antihistamine Non Drowsy Generic Viagra Buy Now Because a similar nonsedating antihistamine was already on the market, the f, More than 100 drugs, including claritin, were already in development when the law was passed these products, known as pipeline drugs. As schering-plough holds the generics at bay with one hand, it had hoped to receive f, Because of growing concerns about the two other nonsedating antihistamines. Seldanes manufacturer, marion merrell dow, sent letters to doctors warning of these potentially fatal drug interactions, and in 1992 the f. Generic drug companies typically gear up to produce a cheap version of a drug about five to seven years before a patent is due to expire.
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    What innovative new drugs does schering, for example, have in the pipeline, subsidized by the billions of dollars earned from claritin? Financial analysts are mixed on the companys potential treatments -- for cancer, asthma, high cholesterol and several other major diseases -- but a leading candidate for future blockbuster status is. The little white pill was easy to swallow and had to be taken only once a day. The other reason is that were just bloody-minded about it, quite frankly. A patent lasted 17 years from the date it was issued it now lasts 20 years from the date the application is filed. Much of the industrys current disgruntlement involves patent litigation -- or as george s.

    There are no villains, no broken laws -- just an enormous expenditure of money, a highly sophisticated understanding of food and drug laws, daring marketing, a great deal of luck. The claritin story is an unauthorized biography, in the sense that schering-plough declined to grant any interviews and responded only to written questions. For all the closed-door maneuvering in washington, an equally revealing pharmaceutical endgame has been playing out, slowly, in a courtroom in new jersey. They were smooth, round yellow tablets, etched with a tiny red corporate symbol that was as delicate as a chinese ideograph. July 1989, as the general accounting office report puts it, a consensus had developed at f.

    As a result, each attempt by the company to get congressional patent relief has become a rallying cry for opponents, including consumer watchdogs, health insurers and generic drug makers. The first-generation antihistamines, now sold over the counter as chlor-trimeton, benadryl, tavist and others, are still considered pretty effective medicines. Anthony nicholson, a british neuroscientist, one of the schering-sponsored clinical researchers, over the interpretation of a study that compared loratadine to a sedating antihistamine called tripolidine. The moment the first generic enters the market, industry experts estimate, the cost of generic claritin will drop to about 80 percent of current prices. Loratadine (claritin), dosing, proper use and what to know before beginning treatment, imagespage see images of loratadine (claritin), including the medication and its packaging, latestnewspage news and savings tips created by doctors and pharmacists for loratadine (claritin), savingspage tips and ways to save for loratadine (claritin), defaultimage httpsd4fuqqd5l3dbz. Save up to 80 instantly!, sideeffectspage learn about side effects and possible interactions when taking loratadine (claritin), medicareseopage medicare coverage and pricing details for loratadine. The popular antihistamines are valuable at preventing an allergy attack from getting under way if taken ahead of time and seem to be effective against eye symptoms, but they rarely bring quick and substantial relief of nasal symptoms once histamine has already begun to wreak havoc. The industry has developed many remarkable medicines, and more are on the way. Generic drug companies typically gear up to produce a cheap version of a drug about five to seven years before a patent is due to expire. Only about 30 to 40 percent of his patients, he said, found the drug helpful.

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